Baltimore finalizes its Jacoby Brissett trade, Cleveland names Shedeur Sanders its starter, and Brandon Aiyuk meets with San Francisco.
Jacksonville dominates Baltimore on Thursday Night Football, Lamar Jackson lands on injured reserve, and Minnesota turns to Carson Wentz.
Chicago trades two first-round picks for Jeffery Simmons, Green Bay defeats Carolina, and A.J. Brown faces another injury setback.
Caleb Williams moves closer to returning, Marvin Harrison Jr. will debut for Houston and Lamar Jackson remains day-to-day entering Week 6.
Roger Goodell signs through 2030, the Giants extend Jameis Winston and Jon Runyan, and the Rams get encouraging Week 1 injury news.
Harrison Smith returns to Minnesota, TreVeyon Henderson remains sidelined and Seattle adds safety depth before the NFL season opener.